Category Archives: Tom 19-1
Epigenetic «probes» for lung cancer monitoring: LINE-1 methylation pattern in blood- circulating DNA. A. A. Ponomaryova, Е. Y. Rykova, N. V. Cherdyntseva, A. A. Bondar, A. Y. Dobrodeev, A. A. Zavyalov, S. A. Tuzikov, L. O. Bryzgalov, T. I. Merkulova, V. V. Vlassov, P. P. Laktionov
Abstract: Malignant cell transformation is accompanied by two processes of DNA methylation changes: promoter hypermethylation of specific genes and hypomethylation of retrotransposons. The composition of circulating DNA (cirDNA) from plasma and cell-surface-bound circulating DNA (csb- cirDNA) was shown earlier to be altered …
Induction of tyrosine aminotransferase in mice is inhibited by activated metabolites of ortho- aminoazotoluene. V. I. Kaledin, S. I. Ilnitskaya, N. A. Popova, O. A. Koval, I. A. Pyshnaya, L. F. Gulyaeva
Abstract: Aminoazo dyes and other hepatocarcinogenic substances inhibit glucocorticoid-mediated induction of adaptive enzymes, including tyrosine aminotransferase (TAT), in mouse and rat liver. There is a specific relationship between the effect of a carcinogen on TAT induction and its liver carcinogenicity in …
Some limitations in the use of the mitochondrial DNA cytb gene as a molecular marker for phylogenetic and population genetic studies by the example of the Apodemus genus. A. G. Lapinski, M. V. Pavlenko, L. L. Solovenchuk, V. V. Gorbachev
Abstract: The interpretation of a signal sent by the mtDNA cytb gene as a molecular marker in phylogenetic and population genetic research can be complicated by cumulative influence of parallel mutations, i.e., the entropy of nucleotide sequences. Such a phenomenon impedes …
The metabolomic approach to the assessment of cultivar specificity of Brassica napus L. seeds. G. N. Smolikova, A. L. Shavarda, I. V. Alekseichuk, V. V. Chantseva, S. S. Medvedev
Abstract: Recent biomolecular studies tend to involve combinations of different methods and approaches that allow analyzing organisms on the genomic and proteomic levels, as well as on the level of metabolomics. However, in order to justify the use of the metabolomics techniques …
Doubled haploid production in Brassica L. N. A. Shmykova, D. V. Shumilina, T. P. Suprunova
Abstract: Doubled haploids (DHs) production through androgenesis is a biotechnological method for genetic improvement of crops. Biotechnological DH line production offers advantages to plant breeders, including the possibility to obtain homozygous lines within a year in contrast to common inbreeding …
Apple gene pool use, sources and donors of economically valuable traits. E. N. Sedov
Abstract: The significance of an apple genetic collection and its use in the development of new adaptive apple cultivars meeting up-to-date requirements are investigated. Nevertheless, the genetic diversity of existing collections is shown to be still insufficiently used in breeding …
Absence of genetic introgression between Elymus ciliaris and E. pendulinus (Triticeae: Poaceae) as shown by endosperm protein SDS-electrophoresis in connection with hypotheses of E. amurensis origin. A. V. Agafonov, E. V. Kobozeva, S. I. Tatkov
Abstract: The StY-genome group of Elymus species is of special interest, most of its species ranges extending to Russia from southern frontier territories, mainly from China. The ranges of Elymus pendulinus, E. ciliaris and E. amurensis within Russia overlap in the southern part …
Raise of short-stemmed vaviloid branched spike lines and their cytogenetics. A. J. Aliyeva, S. P. Mehdiyeva, R. K. Kerimova
Abstract: Hybridization between hexaploid species of wheat (Triticum L.) and triticale (Ч Triticosecale Wittm.) is used widely in genetic research and breeding when studying mutual introgressions of genetic material to original species. As far as the hexaploid triticale obtained in …
Introgression of common wheat lines with genetic material of Agropyron glaucum. R. O. Davoyan, I. V. Bebyakina, E. R. Davoyan, A. N. Zinchenco, Y. S. Zubanova, D. S. Mikov
Abstract: Grey wheatgrass Agropyron glaucum (Desf. ex DC) Roem. & Schult is a valuable source of genes for resistance to diseases, frost resistance, and salt tolerance. An unstable 76-chromosomal amphidiploid combining genomes A and B of common wheat variety Avrora, six chromosomes …
Kazakhstan-Siberian spring common wheat identification according to glutenin and gliadin composition. A. I. Abugalieva, A. I. Morgunov, J. R. Pena, N. B. Volkovinskaya, T. V. Savin
Abstract: Within ten years, the Kazakhstan-Siberian nursery net for spring common wheat improvement (KASIB) working under the auspices of CIMMYT (Intenational Maize and Wheat Improvement Center) characterized accessions of five cultivar blocks with regard to the compositions of gliadin (1B/1R translocation), …